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KMID : 0377619710210060531
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Korean Jungang Medical Journal
1971 Volume.21 No. 6 p.531 ~ p.533
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L-Dopa Treatment of Parkinsonism and Torsiondystonia-Torticollis
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Abstract
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Eight Parkinsonism cases and 1 case of torsion dystonia with torticollis were treated with L-Dopa according to the schedule shown in the table 1.
All cases except 1 Parkinsom and I non Parkinsonism showed slight to moderate improvement but they all showed various side reactions, such as nausea, headache, anorexia, palpitation, dizziness, agitation etc. One patient complained of his tremor increased.
Because of the little dosage at the initial stage of the therapy, all patients
who used to take pargitane, asked for pargitane to get rid of the ailment. Pargitane dosage was gradually tapered off as the dosage of L-Dopa was gradually increased.
However even after 4-5th week when pargitane was completely off, all patient except 1, stated no better effect with L-Dopa compared to pargitane. The one case stated almost the same effect except the side reactions.
The case of torsion dystonia with torticollis was treated for 15 weeks but he showed no definite improvement.
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